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Comparison of variance estimators for meta-analysis of instrumental variable estimates
Background: Mendelian randomization studies perform instrumental variable (IV) analysis using genetic IVs. Results of individual Mendelian randomization studies can be pooled through meta-analysis. We explored how different variance estimators influence the meta-analysed IV estimate. Methods: Two ve...
Autores principales: | Schmidt, AF, Hingorani, AD, Jefferis, BJ, White, J, Groenwold, RHH, Dudbridge, F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654757/ https://www.ncbi.nlm.nih.gov/pubmed/27591262 http://dx.doi.org/10.1093/ije/dyw123 |
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