BCL-X(L) directly modulates RAS signalling to favour cancer cell stemness

In tumours, accumulation of chemoresistant cells that express high levels of anti-apoptotic proteins such as BCL-X(L) is thought to result from the counter selection of sensitive, low expresser clones during progression and/or initial treatment. We herein show that BCL-X(L) expression is selectively...

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Detalles Bibliográficos
Autores principales: Carné Trécesson, Sophie de, Souazé, Frédérique, Basseville, Agnès, Bernard, Anne-Charlotte, Pécot, Jessie, Lopez, Jonathan, Bessou, Margaux, Sarosiek, Kristopher A., Letai, Anthony, Barillé-Nion, Sophie, Valo, Isabelle, Coqueret, Olivier, Guette, Catherine, Campone, Mario, Gautier, Fabien, Juin, Philippe Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654832/
https://www.ncbi.nlm.nih.gov/pubmed/29066722
http://dx.doi.org/10.1038/s41467-017-01079-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654832/
https://www.ncbi.nlm.nih.gov/pubmed/29066722
http://dx.doi.org/10.1038/s41467-017-01079-1

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