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Structural basis for the bacterial membrane insertion of dermcidin peptide, DCD-1L
Human dermcidin (DCD) is an antimicrobial peptide secreted constitutively by sweat glands. The anionic derivative, DCD-1L, comprises of the N-terminal 47 residues of DCD and one additional leucine residue. A previous NMR structure of DCD-1L in 50% TFE showed a partial helical conformation, and its c...
Autores principales: | Nguyen, Van Sang, Tan, Kang Wei, Ramesh, Karthik, Chew, Fook Tim, Mok, Yu Keung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654962/ https://www.ncbi.nlm.nih.gov/pubmed/29066724 http://dx.doi.org/10.1038/s41598-017-13600-z |
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