Ghrelin rescues skeletal muscle catabolic profile in the R6/2 mouse model of Huntington’s disease

Accumulating evidence suggests altered energy metabolism as a key feature in Huntington’s disease (HD) pathology. Hyper-catabolism, including weight loss and muscle atrophy, is seen in HD patients and HD mouse models. Metabolic hormones are key players, not only in energy metabolism, but also in neu...

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Detalles Bibliográficos
Autores principales: Sjögren, Marie, Duarte, Ana I., McCourt, Andrew C., Shcherbina, Liliya, Wierup, Nils, Björkqvist, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654969/
https://www.ncbi.nlm.nih.gov/pubmed/29066728
http://dx.doi.org/10.1038/s41598-017-13713-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654969/
https://www.ncbi.nlm.nih.gov/pubmed/29066728
http://dx.doi.org/10.1038/s41598-017-13713-5

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