Cargando…
Ghrelin rescues skeletal muscle catabolic profile in the R6/2 mouse model of Huntington’s disease
Accumulating evidence suggests altered energy metabolism as a key feature in Huntington’s disease (HD) pathology. Hyper-catabolism, including weight loss and muscle atrophy, is seen in HD patients and HD mouse models. Metabolic hormones are key players, not only in energy metabolism, but also in neu...
Autores principales: | Sjögren, Marie, Duarte, Ana I., McCourt, Andrew C., Shcherbina, Liliya, Wierup, Nils, Björkqvist, Maria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654969/ https://www.ncbi.nlm.nih.gov/pubmed/29066728 http://dx.doi.org/10.1038/s41598-017-13713-5 |
Ejemplares similares
-
Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington’s Disease
por: Duarte, Ana I., et al.
Publicado: (2018) -
Ghrelin Is a Regulator of Glucagon-Like Peptide 1 Secretion and Transcription in Mice
por: Lindqvist, Andreas, et al.
Publicado: (2017) -
White Adipose Tissue Browning in the R6/2 Mouse Model of Huntington’s Disease
por: McCourt, Andrew C., et al.
Publicado: (2016) -
Characterization of Gastric Mucosa Biopsies Reveals Alterations in Huntington's Disease
por: McCourt, Andrew C, et al.
Publicado: (2015) -
Increased intestinal permeability and gut dysbiosis in the R6/2 mouse model of Huntington’s disease
por: Stan, Tiberiu Loredan, et al.
Publicado: (2020)