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Structural, physicochemical and dynamic features conserved within the aerolysin pore-forming toxin family

Aerolysin is the founding member of a major class of β-pore-forming toxins (β-PFTs) found throughout all kingdoms of life. PFTs are cytotoxic proteins produced as soluble monomers, which oligomerize at the membrane of target host cells forming pores that may lead to osmotic lysis and cell death. Bes...

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Detalles Bibliográficos
Autores principales: Cirauqui, Nuria, Abriata, Luciano A., van der Goot, F. Gisou, Dal Peraro, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654971/
https://www.ncbi.nlm.nih.gov/pubmed/29066778
http://dx.doi.org/10.1038/s41598-017-13714-4