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Peripheral CD19(hi) B cells exhibit activated phenotype and functionality in promoting IgG and IgM production in human autoimmune diseases

Systemic Lupus Erythematosus (SLE) and pemphigus are two representative autoimmune diseases driven by pathogenic autoantibody systemically and organ-specifically, respectively. Given the involvement of antibody in the pathogenesis, B cells are inclined to differentiate and function in an abnormal ac...

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Detalles Bibliográficos
Autores principales: Liu, Zhicui, Zeng, Weihong, Huang, Xiangyang, Wang, Shujun, Zheng, Jie, Pan, Meng, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655037/
https://www.ncbi.nlm.nih.gov/pubmed/29066741
http://dx.doi.org/10.1038/s41598-017-14089-2