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Peripheral CD19(hi) B cells exhibit activated phenotype and functionality in promoting IgG and IgM production in human autoimmune diseases
Systemic Lupus Erythematosus (SLE) and pemphigus are two representative autoimmune diseases driven by pathogenic autoantibody systemically and organ-specifically, respectively. Given the involvement of antibody in the pathogenesis, B cells are inclined to differentiate and function in an abnormal ac...
Autores principales: | Liu, Zhicui, Zeng, Weihong, Huang, Xiangyang, Wang, Shujun, Zheng, Jie, Pan, Meng, Wang, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655037/ https://www.ncbi.nlm.nih.gov/pubmed/29066741 http://dx.doi.org/10.1038/s41598-017-14089-2 |
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