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Antagonism between Front-Line Antibiotics Clarithromycin and Amikacin in the Treatment of Mycobacterium abscessus Infections Is Mediated by the whiB7 Gene

Combinations of antibiotics, each individually effective against Mycobacterium abscessus, are routinely coadministered based on the concept that this minimizes the spread of antibiotic resistance. However, our in vitro data contradict this assumption and instead document antagonistic interactions be...

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Detalles Bibliográficos
Autores principales: Pryjma, Mark, Burian, Ján, Kuchinski, Kevin, Thompson, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655113/
https://www.ncbi.nlm.nih.gov/pubmed/28874379
http://dx.doi.org/10.1128/AAC.01353-17