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Structure of RNA polymerase bound to ribosomal 30S subunit

In bacteria, mRNA transcription and translation are coupled to coordinate optimal gene expression and maintain genome stability. Coupling is thought to involve direct interactions between RNA polymerase (RNAP) and the translational machinery. We present cryo-EM structures of E. coli RNAP core bound...

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Detalles Bibliográficos
Autores principales: Demo, Gabriel, Rasouly, Aviram, Vasilyev, Nikita, Svetlov, Vladimir, Loveland, Anna B, Diaz-Avalos, Ruben, Grigorieff, Nikolaus, Nudler, Evgeny, Korostelev, Andrei A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655137/
https://www.ncbi.nlm.nih.gov/pubmed/29027901
http://dx.doi.org/10.7554/eLife.28560