Deletion of tumor suppressors adenomatous polyposis coli and Smad4 in murine luminal epithelial cells causes invasive prostate cancer and loss of androgen receptor expression

Prostate cancer is the most diagnosed non-skin cancer in the US and kills approximately 27,000 men per year in the US. Additional genetic mouse models are needed that recapitulate the heterogeneous nature of human prostate cancer. The Wnt/beta-catenin signaling pathway is important for human prostat...

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Detalles Bibliográficos
Autores principales: Valkenburg, Kenneth C., De Marzo, Angelo M., Williams, Bart O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655195/
https://www.ncbi.nlm.nih.gov/pubmed/29113300
http://dx.doi.org/10.18632/oncotarget.17919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655195/
https://www.ncbi.nlm.nih.gov/pubmed/29113300
http://dx.doi.org/10.18632/oncotarget.17919

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