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Overexpression of microRNA-132 enhances the radiosensitivity of cervical cancer cells by down-regulating Bmi-1

We examined the effects of microRNA-132 (miR-132) on Bmi-1 expression and radiosensitivity in HeLa, SiHa, and C33A cervical cancer (CC) cells and 104 CC patients. MiR-132 expression was decreased and Bmi-1 expression was increased in tumor tissues compared to adjacent normal tissues and in radiother...

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Detalles Bibliográficos
Autores principales: Liu, Gui-Feng, Zhang, Shu-Hua, Li, Xue-Feng, Cao, Li-Yan, Fu, Zhan-Zhao, Yu, Shao-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655237/
https://www.ncbi.nlm.nih.gov/pubmed/29113342
http://dx.doi.org/10.18632/oncotarget.20358