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Affecting long-term fear memory formation through optical control of Rac1 GTPase and PAK activity in lateral amygdala

Fear conditioning, a behavioral model for studying fear-related disorders, is believed to be formed by alterations of synaptic efficacy mediated by changes in synaptic transmission and neuronal morphology in lateral amygdala (LA). Rac GTPase and its downstream effector p21-activated kinase (PAK) are...

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Detalles Bibliográficos
Autores principales: Das, Aniruddha, Dines, Monica, Alapin, Jessica M., Lamprecht, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655381/
https://www.ncbi.nlm.nih.gov/pubmed/29066727
http://dx.doi.org/10.1038/s41598-017-13674-9