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Nicotinamide-based diamides derivatives as potential cytotoxic agents: synthesis and biological evaluation

A series of diamides derivatives containing nicotinamide unit were designed, synthesized and evaluated for their potential cytotoxic activities against human cancer cell lines. All the synthesized compounds were characterized using spectroscopic methods mainly including (1)H NMR, (13)C NMR and MS. T...

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Detalles Bibliográficos
Autores principales: Peng, Min, Shi, Liqiao, Ke, Shaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655388/
https://www.ncbi.nlm.nih.gov/pubmed/29086880
http://dx.doi.org/10.1186/s13065-017-0338-5