Impact of Inverted Terminal Repeat Integrity on rAAV8 Production Using the Baculovirus/Sf9 Cells System

Adeno-associated virus (AAV) inverted terminal repeats (ITRs) are key elements of AAV. These guanine-cytosine-rich structures are involved in the replication and encapsidation of the AAV genome, along with its integration in and excision from the host genome. These sequences are the only AAV-derived...

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Detalles Bibliográficos
Autores principales: Savy, Adrien, Dickx, Yohann, Nauwynck, Lucile, Bonnin, Delphine, Merten, Otto-Wilhelm, Galibert, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655423/
https://www.ncbi.nlm.nih.gov/pubmed/28967288
http://dx.doi.org/10.1089/hgtb.2016.133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655423/
https://www.ncbi.nlm.nih.gov/pubmed/28967288
http://dx.doi.org/10.1089/hgtb.2016.133

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