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Zinc-finger protein 418 overexpression protects against cardiac hypertrophy and fibrosis

BACKGROUND: This study aimed to investigated the effect and mechanism of zinc-finger protein 418 (ZNF418) on cardiac hypertrophy caused by aortic banding (AB), phenylephrine (PE) or angiotensin II (Ang II) in vivo and in vitro. METHODS: The expression of ZNF418 in hearts of patients with dilated car...

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Detalles Bibliográficos
Autores principales: Pan, Liming, Sheng, Mengting, Huang, Zirui, Zhu, Zhilin, Xu, Chunli, Teng, Lin, He, Ling, Gu, Chen, Yi, Cai, Li, Junming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655480/
https://www.ncbi.nlm.nih.gov/pubmed/29065170
http://dx.doi.org/10.1371/journal.pone.0186635