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MGMT and MSH6 immunoexpression for functioning pituitary macroadenomas

PURPOSE: Knowledge of biological behavior is crucial for clinical management of functioning pituitary macroadenomas. For recurrent cases unresponsive to standard treatment, temozolomide (TMZ) has been used as a therapeutic alternative. MGMT (O6-methyl-guanine-DNA methyltransferase) and MSH6 (mutS ho...

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Detalles Bibliográficos
Autores principales: Micko, Alexander S. G., Wöhrer, Adelheid, Höftberger, Romana, Vila, Greisa, Marosi, Christine, Knosp, Engelbert, Wolfsberger, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655586/
https://www.ncbi.nlm.nih.gov/pubmed/28900805
http://dx.doi.org/10.1007/s11102-017-0829-3