Gene isoforms as expression-based biomarkers predictive of drug response in vitro

Next-generation sequencing technologies have recently been used in pharmacogenomic studies to characterize large panels of cancer cell lines at the genomic and transcriptomic levels. Among these technologies, RNA-sequencing enable profiling of alternatively spliced transcripts. Given the high freque...

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Detalles Bibliográficos
Autores principales: Safikhani, Zhaleh, Smirnov, Petr, Thu, Kelsie L., Silvester, Jennifer, El-Hachem, Nehme, Quevedo, Rene, Lupien, Mathieu, Mak, Tak W., Cescon, David, Haibe-Kains, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655668/
https://www.ncbi.nlm.nih.gov/pubmed/29066719
http://dx.doi.org/10.1038/s41467-017-01153-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655668/
https://www.ncbi.nlm.nih.gov/pubmed/29066719
http://dx.doi.org/10.1038/s41467-017-01153-8

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