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Gene isoforms as expression-based biomarkers predictive of drug response in vitro
Next-generation sequencing technologies have recently been used in pharmacogenomic studies to characterize large panels of cancer cell lines at the genomic and transcriptomic levels. Among these technologies, RNA-sequencing enable profiling of alternatively spliced transcripts. Given the high freque...
Autores principales: | Safikhani, Zhaleh, Smirnov, Petr, Thu, Kelsie L., Silvester, Jennifer, El-Hachem, Nehme, Quevedo, Rene, Lupien, Mathieu, Mak, Tak W., Cescon, David, Haibe-Kains, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655668/ https://www.ncbi.nlm.nih.gov/pubmed/29066719 http://dx.doi.org/10.1038/s41467-017-01153-8 |
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