Familial MTC with RET exon 8 Gly533Cys mutation: origin and prevalence of second malignancy

INTRODUCTION: High prevalence of RET p.Gly533Cys (c.1597G > T) has been found in familial MTC in Greece (exon 8 fMTC). We studied their origin and compared clinical characteristics with non-exon 8 fMTC. METHODS: 102 fMTC (FMTC and MEN2A) patients (31.4% males) were followed for 2.9–37 years (medi...

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Detalles Bibliográficos
Autores principales: Saltiki, Katerina, Anagnostou, Elli, Simeakis, George, Kouki, Sofia, Angelopoulou, Anastasia, Sarika, Leda, Papathoma, Alexandra, Alevizaki, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655672/
https://www.ncbi.nlm.nih.gov/pubmed/28951487
http://dx.doi.org/10.1530/EC-17-0147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655672/
https://www.ncbi.nlm.nih.gov/pubmed/28951487
http://dx.doi.org/10.1530/EC-17-0147

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