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BclI polymorphism of the glucocorticoid receptor and adrenal crisis in primary adrenal insufficiency

CONTEXT: Patients with primary adrenal insufficiency (PAI) or congenital adrenal hyperplasia (CAH) are at a high risk of adrenal crisis (AC). Glucocorticoid sensitivity is at least partially genetically determined by polymorphisms of the glucocorticoid receptor (GR). OBJECTIVES: To determine if a nu...

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Detalles Bibliográficos
Autores principales: Zopf, Kathrin, Frey, Kathrin R, Kienitz, Tina, Ventz, Manfred, Bauer, Britta, Quinkler, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655680/
https://www.ncbi.nlm.nih.gov/pubmed/28954735
http://dx.doi.org/10.1530/EC-17-0269