A monocyte‐TNF‐endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade

Elaboration of tumor necrosis factor (TNF) is a very early event in development of ischemia/reperfusion injury pathophysiology. Therefore, TNF may be a prominent mediator of endothelial cell and vascular wall dysfunction in sickle cell anemia, a hypothesis we addressed using NY1DD, S+S(Antilles), an...

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Detalles Bibliográficos
Autores principales: Solovey, Anna, Somani, Arif, Belcher, John D., Milbauer, Liming, Vincent, Lucile, Pawlinski, Rafal, Nath, Karl A., Kelm, Robert J., Mackman, Nigel, O'Sullivan, M. Gerard, Gupta, Kalpna, Vercellotti, Gregory M., Hebbel, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655742/
https://www.ncbi.nlm.nih.gov/pubmed/28699284
http://dx.doi.org/10.1002/ajh.24856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655742/
https://www.ncbi.nlm.nih.gov/pubmed/28699284
http://dx.doi.org/10.1002/ajh.24856

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