Expansion of BCR/ABL1 (+) cells requires PAK2 but not PAK1

The p21‐activated kinases (PAKs) are key nodes in oncogenic signalling pathways controlling growth, survival, and motility of cancer cells. Their activity is increased in many human cancers and is associated with poor prognosis. To date, PAK deregulation has mainly been studied in solid tumours, whe...

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Detalles Bibliográficos
Autores principales: Edlinger, Leo, Berger‐Becvar, Angelika, Menzl, Ingeborg, Hoermann, Gregor, Greiner, Georg, Grundschober, Eva, Bago‐Horvath, Zsuzsanna, Al‐Zoughbi, Wael, Hoefler, Gerald, Brostjan, Christine, Gille, Lars, Moriggl, Richard, Spittler, Andreas, Sexl, Veronika, Hoelbl‐Kovacic, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Haematological Malignancy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655792/
https://www.ncbi.nlm.nih.gov/pubmed/28707321
http://dx.doi.org/10.1111/bjh.14833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655792/
https://www.ncbi.nlm.nih.gov/pubmed/28707321
http://dx.doi.org/10.1111/bjh.14833

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