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Glucagon-like peptide receptor agonists attenuate advanced glycation end products-induced inflammation in rat mesangial cells

BACKGROUND: Hyperglycemia-induced advanced glycation end products (AGEs) and receptor for AGEs (RAGE) production play major roles in progression of diabetic nephropathy. Anti-RAGE effect of peroxisome proliferator-activated receptor-delta (PPARδ) agonists was shown in previous studies. PPARδ agonist...

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Detalles Bibliográficos
Autores principales: Chang, Jui-Ting, Liang, Yao-Jen, Hsu, Chia-Yu, Chen, Chao-Yi, Chen, Po-Jung, Yang, Yi-Feng, Chen, Yen-Lin, Pei, Dee, Chang, Jin-Biou, Leu, Jyh-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655807/
https://www.ncbi.nlm.nih.gov/pubmed/29065926
http://dx.doi.org/10.1186/s40360-017-0172-3