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Leukemia/lymphoma‐related factor (LRF) exhibits stage‐ and context‐dependent transcriptional controls in the oligodendrocyte lineage and modulates remyelination

Leukemia/lymphoma‐related factor (LRF), a zinc‐finger transcription factor encoded by Zbtb7a, is a protooncogene that regulates differentiation in diverse cell lineages, and in the CNS, its function is relatively unexplored. This study is the first to examine the role of LRF in CNS pathology. We fir...

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Detalles Bibliográficos
Autores principales: Davidson, Nathan L., Yu, Fengshan, Kijpaisalratana, Naruchorn, Le, Tuan Q., Beer, Laurel A., Radomski, Kryslaine L., Armstrong, Regina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655903/
https://www.ncbi.nlm.nih.gov/pubmed/28556945
http://dx.doi.org/10.1002/jnr.24083