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Identification and utilization of two important transporters: SgvT1 and SgvT2, for griseoviridin and viridogrisein biosynthesis in Streptomyces griseoviridis

BACKGROUND: Griseoviridin (GV) and viridogrisein (VG, also referred as etamycin), both biosynthesized by a distinct 105 kb biosynthetic gene cluster (BGC) in Streptomyces griseoviridis NRRL 2427, are a pair of synergistic streptogramin antibiotics and very important in treating infections of many mu...

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Detalles Bibliográficos
Autores principales: Xie, Yunchang, Ma, Junying, Qin, Xiangjing, Li, Qinglian, Ju, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655939/
https://www.ncbi.nlm.nih.gov/pubmed/29065880
http://dx.doi.org/10.1186/s12934-017-0792-8