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Synergistic inhibitory effects of an engineered antibody-like molecule ATF-Fc and trastuzumab on tumor growth and invasion in a human breast cancer xenograft mouse model

The overexpression of the oncogene human epidermal growth factor receptor 2 (HER-2) has been associated with decreased disease-free survival and is a marker of poor prognosis of invasive breast cancer. Although the high efficacy of trastuzumab, a drug that targets the HER-2 oncogene, has been widely...

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Detalles Bibliográficos
Autores principales: Zhou, Hongwei, Wang, Hongwei, Yu, Guangyuan, Wang, Zhihong, Zheng, Xi, Duan, Haifeng, Sun, Junzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656026/
https://www.ncbi.nlm.nih.gov/pubmed/29113154
http://dx.doi.org/10.3892/ol.2017.6896