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Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications

Physiologically based kinetic (PBK) models are used widely throughout a number of working sectors, including academia and industry, to provide insight into the dosimetry related to observed adverse health effects in humans and other species. Use of these models has increased over the last several de...

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Detalles Bibliográficos
Autores principales: Paini, Alicia, Leonard, Jeremy A., Kliment, Tomas, Tan, Yu-Mei, Worth, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656087/
https://www.ncbi.nlm.nih.gov/pubmed/28866268
http://dx.doi.org/10.1016/j.yrtph.2017.08.019