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Peripheral and orofacial pain sensation is unaffected by the loss of p39

Cdk5 is a key neuronal kinase necessary for proper brain development, which has recently been implicated in modulating nociception. Conditional deletion of Cdk5 in pain-sensing neurons attenuates pain responses to heat in both the periphery and orofacial regions. Cdk5 activity is regulated by bindin...

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Detalles Bibliográficos
Autores principales: Prochazkova, Michaela, Hall, Bradford, Hu, Minghan, Okine, Tracy, Reukauf, Jennifer, Binukumar, BK, Amin, Niranjana D, Roque, Eva, Pant, Harish C, Kulkarni, Ashok B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656108/
https://www.ncbi.nlm.nih.gov/pubmed/28969475
http://dx.doi.org/10.1177/1744806917737205