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Conditional deletion of Pip5k1c in sensory ganglia and effects on nociception and inflammatory sensitization

Phosphatidylinositol 4-phosphate 5-kinase type 1 gamma (Pip5k1c) generates phosphatidylinositol 4,5-bisphosphate, also known as PI(4,5)P(2) or PIP(2). Many pronociceptive signaling pathways and receptor tyrosine kinases signal via PIP(2) hydrolysis. Previously, we found that pain signaling and pain...

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Detalles Bibliográficos
Autores principales: Loo, Lipin, Zylka, Mark J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656109/
https://www.ncbi.nlm.nih.gov/pubmed/29020859
http://dx.doi.org/10.1177/1744806917737907