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Forkhead Box Transcription Factors of the FOXA Class Are Required for Basal Transcription of Angiotensin-Converting Enzyme 2

Angiotensin-converting enzyme 2 (ACE2) has protective effects on a wide range of morbidities associated with elevated angiotensin-II signaling. Most tissues, including pancreatic islets, express ACE2 mainly from the proximal promoter region. We previously found that hepatocyte nuclear factors 1α and...

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Detalles Bibliográficos
Autores principales: Pedersen, Kim Brint, Chodavarapu, Harshita, Lazartigues, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656262/
https://www.ncbi.nlm.nih.gov/pubmed/29082356
http://dx.doi.org/10.1210/js.2016-1071