Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis

The sequential use of signaling pathways is essential for the guidance of pluripotent progenitors into diverse cell fates. Here, we show that Shp2 exclusively mediates FGF but not PDGF signaling in the neural crest to control lacrimal gland development. In addition to preventing p53-independent apop...

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Detalles Bibliográficos
Autores principales: Garg, Ankur, Bansal, Mukesh, Gotoh, Noriko, Feng, Gen-Sheng, Zhong, Jian, Wang, Fen, Kariminejad, Ariana, Brooks, Steven, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656309/
https://www.ncbi.nlm.nih.gov/pubmed/29028795
http://dx.doi.org/10.1371/journal.pgen.1007047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656309/
https://www.ncbi.nlm.nih.gov/pubmed/29028795
http://dx.doi.org/10.1371/journal.pgen.1007047

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