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Exploration of human brain tumour metabolism using pairwise metabolite-metabolite correlation analysis (MMCA) of HR-MAS (1)H NMR spectra

METHODS: We quantified 378 HRMAS (1)H NMR spectra of human brain tumours (132 glioblastomas, 101 astrocytomas, 75 meningiomas, 37 oligodendrogliomas and 33 metastases) from the eTumour database and looked for metabolic interactions by metabolite-metabolite correlation analysis (MMCA). RESULTS: All t...

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Detalles Bibliográficos
Autores principales: Madhu, Basetti, Jauhiainen, Alexandra, McGuire, Sean, Griffiths, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656327/
https://www.ncbi.nlm.nih.gov/pubmed/29069098
http://dx.doi.org/10.1371/journal.pone.0185980