FcγRIIA and IIIA polymorphisms predict clinical outcome of trastuzumab-treated metastatic gastric cancer

Trastuzumab has substantial antitumor activity in metastatic gastric cancer. One such mechanism by which it exerts its antitumor activity is antibody-dependent cell-mediated cytotoxicity, which has been reported to be influenced by FcγRIIA and IIIA polymorphisms. This study is the first to assess th...

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Detalles Bibliográficos
Autores principales: Wang, De-shen, Wei, Xiao-li, Wang, Zhi-qiang, Lu, Yun-xin, Shi, Si-mei, Wang, Niu, Qiu, Miao-zhen, Wang, Feng-hua, Wang, Rong-jiao, Li, Yu-hong, Xu, Rui-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656338/
https://www.ncbi.nlm.nih.gov/pubmed/29089776
http://dx.doi.org/10.2147/OTT.S142620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656338/
https://www.ncbi.nlm.nih.gov/pubmed/29089776
http://dx.doi.org/10.2147/OTT.S142620

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