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Phase I Trial of Systemic Administration of Edmonston Strain of Measles Virus, Genetically Engineered to Express the Sodium Iodide Symporter in Patients with Recurrent or Refractory Multiple Myeloma

MV-NIS is an Edmonston-lineage oncolytic measles virus expressing the human sodium-iodide symporter--a means for monitoring by noninvasive imaging of radioiodine. Patients with relapsed, refractory myeloma who had explored all other treatment options were eligible for this Phase I trial. Cohort 1 wa...

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Detalles Bibliográficos
Autores principales: Dispenzieri, Angela, Tong, Caili, LaPlant, Betsy, Lacy, Martha Q., Laumann, Kristina, Dingli, David, Zhou, Yumei, Federspiel, Mark J., Gertz, Morie A., Hayman, Suzanne, Buadi, Francis, O’Connor, Michael, Lowe, Val J., Peng, Kah-Whye, Russell, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656536/
https://www.ncbi.nlm.nih.gov/pubmed/28439108
http://dx.doi.org/10.1038/leu.2017.120