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Controlled Self-assembly of Stem Cell Aggregates Instructs Pluripotency and Lineage Bias
Stem cell-derived organoids and other 3D microtissues offer enormous potential as models for drug screening, disease modeling, and regenerative medicine. Formation of stem/progenitor cell aggregates is common in biomanufacturing processes and critical to many organoid approaches. However, reproducib...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656593/ https://www.ncbi.nlm.nih.gov/pubmed/29070799 http://dx.doi.org/10.1038/s41598-017-14325-9 |