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Controlled Self-assembly of Stem Cell Aggregates Instructs Pluripotency and Lineage Bias

Stem cell-derived organoids and other 3D microtissues offer enormous potential as models for drug screening, disease modeling, and regenerative medicine. Formation of stem/progenitor cell aggregates is common in biomanufacturing processes and critical to many organoid approaches. However, reproducib...

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Detalles Bibliográficos
Autores principales:	Xie, Angela W., Binder, Bernard Y. K., Khalil, Andrew S., Schmitt, Samantha K., Johnson, Hunter J., Zacharias, Nicholas A., Murphy, William L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656593/ https://www.ncbi.nlm.nih.gov/pubmed/29070799 http://dx.doi.org/10.1038/s41598-017-14325-9

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