Impaired BK(Ca) channel function in native vascular smooth muscle from humans with type 2 diabetes

Large-conductance Ca(2+)-activated potassium (BK(Ca)) channels are key determinants of vascular smooth muscle excitability. Impaired BK(Ca) channel function through remodeling of BK(Ca) β1 expression and function contributes to vascular complications in animal models of diabetes. Yet, whether simila...

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Detalles Bibliográficos
Autores principales: Nieves-Cintrón, Madeline, Syed, Arsalan U., Buonarati, Olivia R., Rigor, Robert R., Nystoriak, Matthew A., Ghosh, Debapriya, Sasse, Kent C., Ward, Sean M., Santana, Luis F., Hell, Johannes W., Navedo, Manuel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656614/
https://www.ncbi.nlm.nih.gov/pubmed/29070899
http://dx.doi.org/10.1038/s41598-017-14565-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656614/
https://www.ncbi.nlm.nih.gov/pubmed/29070899
http://dx.doi.org/10.1038/s41598-017-14565-9

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