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Dual negative roles of C/EBPα in the expansion and pro-tumor functions of MDSCs

Myeloid-derived suppressor cells (MDSCs) are greatly expanded in cancer patients and tumor-bearing mice. They infiltrate into tumors and modulate the tumor microenvironment. In an effort to identify molecular mediators responsible for expansion and the tumor-promoting function of MDSCs, we discovere...

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Detalles Bibliográficos
Autores principales: Mackert, John R., Qu, Peng, Min, Yongfen, Johnson, Peter F., Yang, Li, Lin, P. Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656646/
https://www.ncbi.nlm.nih.gov/pubmed/29070836
http://dx.doi.org/10.1038/s41598-017-12968-2