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Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke

In stroke patients, loss of skeletal muscle mass leads to prolonged weakness and less efficient rehabilitation. We previously showed that expression of myostatin, a master negative regulator of skeletal muscle mass, was strongly increased in skeletal muscle in a mouse model of stroke. We therefore t...

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Detalles Bibliográficos
Autores principales: Desgeorges, Marine Maud, Devillard, Xavier, Toutain, Jérome, Castells, Josiane, Divoux, Didier, Arnould, David Frédéric, Haqq, Christopher, Bernaudin, Myriam, Durieux, Anne-Cécile, Touzani, Omar, Freyssenet, Damien Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656661/
https://www.ncbi.nlm.nih.gov/pubmed/29070788
http://dx.doi.org/10.1038/s41598-017-13912-0