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Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke
In stroke patients, loss of skeletal muscle mass leads to prolonged weakness and less efficient rehabilitation. We previously showed that expression of myostatin, a master negative regulator of skeletal muscle mass, was strongly increased in skeletal muscle in a mouse model of stroke. We therefore t...
Autores principales: | Desgeorges, Marine Maud, Devillard, Xavier, Toutain, Jérome, Castells, Josiane, Divoux, Didier, Arnould, David Frédéric, Haqq, Christopher, Bernaudin, Myriam, Durieux, Anne-Cécile, Touzani, Omar, Freyssenet, Damien Gilles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656661/ https://www.ncbi.nlm.nih.gov/pubmed/29070788 http://dx.doi.org/10.1038/s41598-017-13912-0 |
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