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Increasing Dietary Medium-Chain Fatty Acid Ratio Mitigates High-fat Diet-Induced Non-Alcoholic Steatohepatitis by Regulating Autophagy

Previous studies have demonstrated that saturated fatty acids (SFAs) are more lipotoxic than unsaturated fatty acids (UFAs) in inhibiting hepatic autophagy and promoting non-alcoholic steatohepatitis (NASH). However, there have been few studies have investigated the effects of carbon chain length on...

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Detalles Bibliográficos
Autores principales: Wang, Mu-En, Singh, Brijesh K., Hsu, Meng-Chieh, Huang, Chien, Yen, Paul M., Wu, Leang-Shin, Jong, De-Shien, Chiu, Chih-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656678/
https://www.ncbi.nlm.nih.gov/pubmed/29070903
http://dx.doi.org/10.1038/s41598-017-14376-y