Clonal Heterogeneity Influences the Fate of New Adaptive Mutations

The joint contribution of pre-existing and de novo genetic variation to clonal adaptation is poorly understood but essential to designing successful antimicrobial or cancer therapies. To address this, we evolve genetically diverse populations of budding yeast, S. cerevisiae, consisting of diploid ce...

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Detalles Bibliográficos
Autores principales: Vázquez-García, Ignacio, Salinas, Francisco, Li, Jing, Fischer, Andrej, Barré, Benjamin, Hallin, Johan, Bergström, Anders, Alonso-Perez, Elisa, Warringer, Jonas, Mustonen, Ville, Liti, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656752/
https://www.ncbi.nlm.nih.gov/pubmed/29045840
http://dx.doi.org/10.1016/j.celrep.2017.09.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656752/
https://www.ncbi.nlm.nih.gov/pubmed/29045840
http://dx.doi.org/10.1016/j.celrep.2017.09.046

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