Cargando…
Clonal Heterogeneity Influences the Fate of New Adaptive Mutations
The joint contribution of pre-existing and de novo genetic variation to clonal adaptation is poorly understood but essential to designing successful antimicrobial or cancer therapies. To address this, we evolve genetically diverse populations of budding yeast, S. cerevisiae, consisting of diploid ce...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656752/ https://www.ncbi.nlm.nih.gov/pubmed/29045840 http://dx.doi.org/10.1016/j.celrep.2017.09.046 |