Melatonin limits paclitaxel‐induced mitochondrial dysfunction in vitro and protects against paclitaxel‐induced neuropathic pain in the rat

Chemotherapy‐induced neuropathic pain is a debilitating and common side effect of cancer treatment. Mitochondrial dysfunction associated with oxidative stress in peripheral nerves has been implicated in the underlying mechanism. We investigated the potential of melatonin, a potent antioxidant that p...

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Detalles Bibliográficos
Autores principales: Galley, Helen F., McCormick, Barry, Wilson, Kirsten L., Lowes, Damon A., Colvin, Lesley, Torsney, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656911/
https://www.ncbi.nlm.nih.gov/pubmed/28833461
http://dx.doi.org/10.1111/jpi.12444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656911/
https://www.ncbi.nlm.nih.gov/pubmed/28833461
http://dx.doi.org/10.1111/jpi.12444

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