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Melatonin limits paclitaxel‐induced mitochondrial dysfunction in vitro and protects against paclitaxel‐induced neuropathic pain in the rat
Chemotherapy‐induced neuropathic pain is a debilitating and common side effect of cancer treatment. Mitochondrial dysfunction associated with oxidative stress in peripheral nerves has been implicated in the underlying mechanism. We investigated the potential of melatonin, a potent antioxidant that p...
Autores principales: | Galley, Helen F., McCormick, Barry, Wilson, Kirsten L., Lowes, Damon A., Colvin, Lesley, Torsney, Carole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656911/ https://www.ncbi.nlm.nih.gov/pubmed/28833461 http://dx.doi.org/10.1111/jpi.12444 |
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