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The γ (c) family of cytokines: fine-tuning signals from IL-2 and IL-21 in the regulation of the immune response

Interleukin (IL)-2, IL-4, IL-7, IL-9, IL-15, and IL-21 form a family of cytokines based on the sharing of a receptor component, the common cytokine receptor γ chain, γ (c), which is encoded by the gene mutated in humans with X-linked severe combined immunodeficiency (XSCID). Together, these cytokine...

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Detalles Bibliográficos
Autores principales: Spolski, Rosanne, Gromer, Daniel, Leonard, Warren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657018/
https://www.ncbi.nlm.nih.gov/pubmed/29123649
http://dx.doi.org/10.12688/f1000research.12202.1