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MegaGTA: a sensitive and accurate metagenomic gene-targeted assembler using iterative de Bruijn graphs

BACKGROUND: The recent release of the gene-targeted metagenomics assembler Xander has demonstrated that using the trained Hidden Markov Model (HMM) to guide the traversal of de Bruijn graph gives obvious advantage over other assembly methods. Xander, as a pilot study, indeed has a lot of room for im...

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Detalles Bibliográficos
Autores principales: Li, Dinghua, Huang, Yukun, Leung, Chi-Ming, Luo, Ruibang, Ting, Hing-Fung, Lam, Tak-Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657035/
https://www.ncbi.nlm.nih.gov/pubmed/29072142
http://dx.doi.org/10.1186/s12859-017-1825-3