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Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice

BACKGROUND: Spinal cord injury (SCI) is a devastating disease, which results in tissue loss and neurologic dysfunction. NLRP3 inflammasome plays an important role in the mechanism of diverse diseases. However, no studies have demonstrated the role of NLRP3 inflammasome and the effects of NLRP3 infla...

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Detalles Bibliográficos
Autores principales: Jiang, Wu, Li, Maoqiang, He, Fan, Zhou, Shaobo, Zhu, Liulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657095/
https://www.ncbi.nlm.nih.gov/pubmed/29070054
http://dx.doi.org/10.1186/s12974-017-0980-9