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LncRNA RP11-436H11.5, functioning as a competitive endogenous RNA, upregulates BCL-W expression by sponging miR-335-5p and promotes proliferation and invasion in renal cell carcinoma

BACKGROUND: Accumulating evidence indicates that long non-coding RNAs (lncRNAs) play a crucial role in tumorigenesis. Here, we report a novel lncRNA, RP11-436H11.5, that regulates renal cell carcinoma (RCC) cell proliferation and invasion by sponging miR-335-5p. METHODS: Expression of lncRNA RP11-43...

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Detalles Bibliográficos
Autores principales: Wang, Kefeng, Jin, Wei, Song, Yan, Fei, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657097/
https://www.ncbi.nlm.nih.gov/pubmed/29070041
http://dx.doi.org/10.1186/s12943-017-0735-3